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  • : Genomic Instability

Genomic Instability - 18 Studies Found

Completed : A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors
:
  • Solid Tumor
  • Microsatellite Instability-High (MSI-H) Solid Tumors
  • Drug: LY3300054 Administered I

Completed : Study of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177)
: Colorectal Carcinoma
: 2015-09-28
:
  • Drug: mFOLFOX6 Regimen consist

Active, not recruiting : Study of Pembrolizumab (MK-3475) as Monotherapy in Participants With Previously-Treated Locally Advanced Unresectable or Metastatic Colorectal Cancer (MK-3475-164/KEYNOTE-164)
: Colorectal Carcinoma
: 2015-05-29
: Biological: Pembrolizumab IV infusion Other Names:
Completed : A Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of Pembrolizumab (MK-3475) in Combination With Epacadostat (INCB024360) in Subjects With Selected Cancers (INCB 24360-202 / MK-3475-037 / KEYNOTE-037/ ECHO-202)
:
  • Malignant Solid Tumor
  • Lymphoma, Large B-Cell, Diffuse
  • Carc
    : 2014-06-26
    :
    • Drug: MK-3475 IV infusion

Completed : Molecular Biology of Anal Cancer in HIV-Positive Patients
:
  • Carcinoma
  • HIV Infections

: 2009-08-03
Completed : Efficacy and Safety of Olaparib in Pretreated Patients With Measurable Colorectal Cancer, Stratified by Microsatellite Instability (MSI) Status
: Colorectal Cancer
: 2009-05-28
: Drug: olaparib 400 mg po bid continuously
Completed : Genetic Study of Young Patients With Colorectal Cancer
: Colorectal Cancer
: 2002-09-06
: Genetic: microsatellite instability analysis
Completed : Deciphering Antitumour Response and Resistance With INtratumour Heterogeneity
: Non-small Cell Lung Cancer
: 2014-12-05
:
  • Drug: MPDL3280A Intravenous (I

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